Drug reference

succinylcholine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (Muscle Relaxants)

Mechanism of action

Depolarizing skeletal muscle relaxant; depolarizes motor endplate at myoneural junction, which causes sustained flaccid skeletal muscle paralysis; no effect on consciousness, pain

Common side effects

  • Jaw rigidity
  • Bradycardia
  • Hypotension
  • Respiratory depression
  • Apnea

Contraindications

  • Hypersensitivity to drug or component; known or suspected genetic susceptibility to malignant hyperthermia, lack of ventilatory support, history of malignant hyperthermia, myopathies associated with elevated serum creatine kinase, acute phase of injury following major burns (hyperkalemia may occur)…

Related conditions

Frequently asked questions

What drug class is succinylcholine?

succinylcholine belongs to: Musculoskeletal.

How does succinylcholine work?

Depolarizing skeletal muscle relaxant; depolarizes motor endplate at myoneural junction, which causes sustained flaccid skeletal muscle paralysis; no effect on consciousness, pain

What are the common side effects of succinylcholine?

Jaw rigidity, Bradycardia, Hypotension, Respiratory depression, Apnea

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