Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Bitter melon
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Bitter melon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Bitter melon may lower potassium or blood glucose in some reports, and thiazide diuretics also cause potassium loss. Together they could increase the chance of hypokalemia, although data are limited.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Bitter melon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive potassium loss; mechanism not firmly established.
What to do
Monitor serum potassium in patients using bitter melon products with hydrochlorothiazide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Bitter melon?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Bitter melon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bitter melon may lower potassium or blood glucose in some reports, and thiazide diuretics also cause potassium loss. Together they could increase the chance of hypokalemia, although data are limited.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Bitter melon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients using bitter melon products with hydrochlorothiazide.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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