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Drug interactions

Amlodipine-olmesartan-hydrochlorothiazide + Budesonide

Severity: Minor

Amlodipine-olmesartan-hydrochlorothiazide and Budesonide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Hydrochlorothiazide and corticosteroids both lower potassium, so combined use may cause hypokalemia. The risk is greater with systemic budesonide and lower with inhaled or locally acting forms.

What this interaction means in plain words

Amlodipine-olmesartan-hydrochlorothiazide and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Budesonide belongs to Respiratory.

Evidence level: Moderate

Why it happens

Additive potassium loss from thiazide kaliuresis and corticosteroid mineralocorticoid activity.

What to do

Monitor serum potassium, particularly with oral or prolonged systemic budesonide, and supplement as needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-olmesartan-hydrochlorothiazide with Budesonide?

MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide and corticosteroids both lower potassium, so combined use may cause hypokalemia. The risk is greater with systemic budesonide and lower with inhaled or locally acting forms.

How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Budesonide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, particularly with oral or prolonged systemic budesonide, and supplement as needed.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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