Drug interactions
Amlodipine-valsartan + Cisatracurium
Severity: Minor
Amlodipine-valsartan and Cisatracurium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may enhance and prolong the effect of nondepolarizing neuromuscular blockers. This matters mainly during anesthesia and recovery.
What this interaction means in plain words
Amlodipine-valsartan and Cisatracurium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Cisatracurium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade may reduce presynaptic acetylcholine release, adding to neuromuscular blockade.
What to do
Use train-of-four monitoring and give lower or less frequent doses of cisatracurium if blockade is prolonged.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Cisatracurium
Frequently asked questions
Can I take Amlodipine-valsartan with Cisatracurium?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Cisatracurium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may enhance and prolong the effect of nondepolarizing neuromuscular blockers. This matters mainly during anesthesia and recovery.
How serious is the interaction between Amlodipine-valsartan and Cisatracurium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use train-of-four monitoring and give lower or less frequent doses of cisatracurium if blockade is prolonged.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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