Drug interactions
Amobarbital + Celiprolol
Severity: Minor
Amobarbital and Celiprolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amobarbital may reduce celiprolol exposure and weaken its blood pressure and heart rate effect. The effect is generally modest, as celiprolol is largely eliminated unchanged.
What this interaction means in plain words
Amobarbital and Celiprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Barbiturate-induced hepatic enzyme induction may increase beta-blocker clearance, though celiprolol undergoes limited metabolism.
What to do
Monitor blood pressure and heart rate when starting or stopping the barbiturate. Increase the celiprolol dose if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Frequently asked questions
Can I take Amobarbital with Celiprolol?
MediHelp rates the interaction as minor. Amobarbital and Celiprolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amobarbital may reduce celiprolol exposure and weaken its blood pressure and heart rate effect. The effect is generally modest, as celiprolol is largely eliminated unchanged.
How serious is the interaction between Amobarbital and Celiprolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or stopping the barbiturate. Increase the celiprolol dose if control is lost.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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