Drug interactions
Amobarbital + Gotu kola
Severity: Moderate
Amobarbital and Gotu kola: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gotu kola has sedative properties and may add to the CNS depression of amobarbital. Excess drowsiness and impaired alertness may result.
What this interaction means in plain words
Amobarbital and Gotu kola can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic CNS depression; gotu kola may act on GABAergic pathways.
What to do
Counsel patients to avoid the herbal product or monitor for excessive sedation, and caution against driving.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Frequently asked questions
Can I take Amobarbital with Gotu kola?
MediHelp rates the interaction as moderate. Amobarbital and Gotu kola can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gotu kola has sedative properties and may add to the CNS depression of amobarbital. Excess drowsiness and impaired alertness may result.
How serious is the interaction between Amobarbital and Gotu kola?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid the herbal product or monitor for excessive sedation, and caution against driving.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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