Drug interactions
Amobarbital + Hops
Severity: Moderate
Amobarbital and Hops: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hops has mild sedative effects and may potentiate the CNS depressant action of amobarbital. This can cause increased drowsiness and psychomotor impairment.
What this interaction means in plain words
Amobarbital and Hops can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sedative effects, possibly via GABAergic activity of hops constituents.
What to do
Advise avoiding hops-containing sedative products during barbiturate therapy, or monitor for oversedation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Frequently asked questions
Can I take Amobarbital with Hops?
MediHelp rates the interaction as moderate. Amobarbital and Hops can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hops has mild sedative effects and may potentiate the CNS depressant action of amobarbital. This can cause increased drowsiness and psychomotor impairment.
How serious is the interaction between Amobarbital and Hops?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding hops-containing sedative products during barbiturate therapy, or monitor for oversedation.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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