Drug interactions
Amobarbital + Passion flower
Severity: Moderate
Amobarbital and Passion flower: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Passion flower has sedative and anxiolytic activity and may add to the CNS depression of amobarbital. Increased drowsiness and impaired psychomotor performance are possible.
What this interaction means in plain words
Amobarbital and Passion flower can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects, likely via GABAergic activity.
What to do
Avoid combined use where practical and counsel on drowsiness. Monitor sedation if both are continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amobarbital and Passion flower, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Frequently asked questions
Can I take Amobarbital with Passion flower?
MediHelp rates the interaction as moderate. Amobarbital and Passion flower can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Passion flower has sedative and anxiolytic activity and may add to the CNS depression of amobarbital. Increased drowsiness and impaired psychomotor performance are possible.
How serious is the interaction between Amobarbital and Passion flower?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined use where practical and counsel on drowsiness. Monitor sedation if both are continued.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
