Drug interactions
Amoxapine + Rosiglitazone
Severity: Minor
Amoxapine and Rosiglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic-type antidepressants have occasionally been associated with changes in glucose control, and some may lower blood glucose. Any added effect on rosiglitazone is unpredictable and probably small.
What this interaction means in plain words
Amoxapine and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive effect on glucose regulation; the mechanism is not clearly established.
What to do
No routine change is needed. Check blood glucose after starting or stopping amoxapine in a patient with diabetes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone Major
- Insulin aspart-insulin aspart protamine + Rosiglitazone Major
- Insulin aspart + Rosiglitazone Major
- Insulin degludec / insulin aspart + Rosiglitazone Major
- Insulin degludec-insulin aspart + Rosiglitazone Major
- Insulin degludec-liraglutide + Rosiglitazone Major
Frequently asked questions
Can I take Amoxapine with Rosiglitazone?
MediHelp rates the interaction as minor. Amoxapine and Rosiglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tricyclic-type antidepressants have occasionally been associated with changes in glucose control, and some may lower blood glucose. Any added effect on rosiglitazone is unpredictable and probably small.
How serious is the interaction between Amoxapine and Rosiglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Check blood glucose after starting or stopping amoxapine in a patient with diabetes.
What other medicines interact with Rosiglitazone?
MediHelp also lists interactions of Rosiglitazone with, for example, Insulin aspart protamine / insulin aspart, Insulin aspart-insulin aspart protamine, Insulin aspart. The full list is on the Rosiglitazone page.
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