Drug interactions
Amphotericin b deoxycholate + Magnesium hydroxide
Severity: Minor
Amphotericin b deoxycholate and Magnesium hydroxide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amphotericin B causes renal magnesium wasting and hypomagnesemia. Oral magnesium may partially offset this loss.
What this interaction means in plain words
Amphotericin b deoxycholate and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Amphotericin B-induced renal tubular injury increases urinary magnesium excretion.
What to do
Monitor serum magnesium and potassium during amphotericin B therapy and replace as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Frequently asked questions
Can I take Amphotericin b deoxycholate with Magnesium hydroxide?
MediHelp rates the interaction as minor. Amphotericin b deoxycholate and Magnesium hydroxide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amphotericin B causes renal magnesium wasting and hypomagnesemia. Oral magnesium may partially offset this loss.
How serious is the interaction between Amphotericin b deoxycholate and Magnesium hydroxide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and potassium during amphotericin B therapy and replace as needed.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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