Drug interactions
Anagrelide + Dabigatran etexilate
Severity: Moderate
Anagrelide and Dabigatran etexilate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anagrelide inhibits platelet aggregation and lowers platelet counts, so combining it with dabigatran increases the likelihood of bleeding. Risk is greater when thrombocytopenia is present.
What this interaction means in plain words
Anagrelide and Dabigatran etexilate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anagrelide belongs to Cardiovascular; Dabigatran etexilate belongs to Cardiovascular.
Why it happens
Additive effects on hemostasis through platelet inhibition and thrombin inhibition.
What to do
Monitor platelet counts and watch for bleeding signs. Reassess the need for both agents if bleeding or marked thrombocytopenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anagrelide and Dabigatran etexilate, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Frequently asked questions
Can I take Anagrelide with Dabigatran etexilate?
MediHelp rates the interaction as moderate. Anagrelide and Dabigatran etexilate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anagrelide inhibits platelet aggregation and lowers platelet counts, so combining it with dabigatran increases the likelihood of bleeding. Risk is greater when thrombocytopenia is present.
How serious is the interaction between Anagrelide and Dabigatran etexilate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor platelet counts and watch for bleeding signs. Reassess the need for both agents if bleeding or marked thrombocytopenia develops.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
