Drug interactions
Anagrelide + Isoflurane
Severity: Moderate
Anagrelide and Isoflurane: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents may prolong the QT interval, and anagrelide can also cause tachycardia and arrhythmias. Combined use during anesthesia may raise the risk of ventricular arrhythmia.
What this interaction means in plain words
Anagrelide and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anagrelide belongs to Cardiovascular; Isoflurane belongs to Central Nervous System.
Why it happens
Additive QT prolongation.
What to do
Check baseline ECG and electrolytes before surgery and monitor the ECG intraoperatively. Avoid other QT-prolonging drugs in the same period.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isoflurane
Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Frequently asked questions
Can I take Anagrelide with Isoflurane?
MediHelp rates the interaction as moderate. Anagrelide and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents may prolong the QT interval, and anagrelide can also cause tachycardia and arrhythmias. Combined use during anesthesia may raise the risk of ventricular arrhythmia.
How serious is the interaction between Anagrelide and Isoflurane?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes before surgery and monitor the ECG intraoperatively. Avoid other QT-prolonging drugs in the same period.
What other medicines interact with Isoflurane?
MediHelp also lists interactions of Isoflurane with, for example, Adrenaline-articaine, Amisulpride, Arsenic trioxide. The full list is on the Isoflurane page.
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