Drug interactions
Anagrelide + Salbutamol
Severity: Moderate
Anagrelide and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anagrelide can cause QT prolongation, tachycardia and palpitations, and salbutamol can add to tachycardia and hypokalemia. The combination may increase the risk of arrhythmia in susceptible patients.
What this interaction means in plain words
Anagrelide and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anagrelide belongs to Cardiovascular; Salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation and cardiac stimulation, with possible beta-2 agonist-induced hypokalemia.
What to do
Monitor ECG and check potassium and magnesium in patients with cardiac risk factors. Use the lowest effective salbutamol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Frequently asked questions
Can I take Anagrelide with Salbutamol?
MediHelp rates the interaction as moderate. Anagrelide and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anagrelide can cause QT prolongation, tachycardia and palpitations, and salbutamol can add to tachycardia and hypokalemia. The combination may increase the risk of arrhythmia in susceptible patients.
How serious is the interaction between Anagrelide and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and check potassium and magnesium in patients with cardiac risk factors. Use the lowest effective salbutamol dose.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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