Drug interactions
Anastrozole + Nimodipine
Severity: Minor
Anastrozole and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anastrozole is a weak inhibitor of drug-metabolizing enzymes and no meaningful rise in nimodipine levels has been shown. A clinically important interaction is unlikely.
What this interaction means in plain words
Anastrozole and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Anastrozole belongs to Oncology; Nimodipine belongs to Cardiovascular.
Why it happens
Theoretical weak CYP3A4 inhibition; not established clinically.
What to do
No adjustment is needed. Monitor blood pressure as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Other interactions of Anastrozole
- Anastrozole + Bazedoxifene / conjugated estrogens Contraindicated
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Anastrozole + Conjugated estrogens Contraindicated
- Anastrozole + Estradiol Contraindicated
- Anastrozole + Estrogens conjugated synthetic Contraindicated
- Anastrozole + Estrogens esterified Contraindicated
Frequently asked questions
Can I take Anastrozole with Nimodipine?
MediHelp rates the interaction as minor. Anastrozole and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anastrozole is a weak inhibitor of drug-metabolizing enzymes and no meaningful rise in nimodipine levels has been shown. A clinically important interaction is unlikely.
How serious is the interaction between Anastrozole and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is needed. Monitor blood pressure as usual.
What other medicines interact with Nimodipine?
MediHelp also lists interactions of Nimodipine with, for example, Apalutamide, Carbamazepine, Ceritinib. The full list is on the Nimodipine page.
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