Drug interactions
Anastrozole + Quinidine
Severity: Minor
Anastrozole and Quinidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anastrozole is only a weak in vitro CYP inhibitor and does not meaningfully raise quinidine levels at clinical doses. Both drugs can be associated with QT effects, but the practical interaction is slight.
What this interaction means in plain words
Anastrozole and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Anastrozole belongs to Oncology; Quinidine belongs to Anti Parasitic.
Why it happens
Weak CYP3A4 inhibition by anastrozole is of doubtful clinical relevance.
What to do
No action beyond routine ECG monitoring that quinidine already requires.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Anastrozole
- Anastrozole + Bazedoxifene / conjugated estrogens Contraindicated
- Anastrozole + Bazedoxifene-conjugated estrogens Contraindicated
- Anastrozole + Conjugated estrogens Contraindicated
- Anastrozole + Estradiol Contraindicated
- Anastrozole + Estrogens conjugated synthetic Contraindicated
- Anastrozole + Estrogens esterified Contraindicated
Frequently asked questions
Can I take Anastrozole with Quinidine?
MediHelp rates the interaction as minor. Anastrozole and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anastrozole is only a weak in vitro CYP inhibitor and does not meaningfully raise quinidine levels at clinical doses. Both drugs can be associated with QT effects, but the practical interaction is slight.
How serious is the interaction between Anastrozole and Quinidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action beyond routine ECG monitoring that quinidine already requires.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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