Drug interactions
Anthrax vaccine adsorbed + Oxaliplatin
Severity: Moderate
Anthrax vaccine adsorbed and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaliplatin chemotherapy suppresses the immune system and may reduce antibody response to the anthrax vaccine. Protection may be incomplete if vaccination occurs during or soon before treatment.
What this interaction means in plain words
Anthrax vaccine adsorbed and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Cytotoxic immunosuppression reduces the immune response to vaccination.
What to do
Vaccinate at least 2 weeks before starting chemotherapy when possible. If given during treatment, revaccinate about 3 months after chemotherapy is completed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Anthrax vaccine adsorbed with Oxaliplatin?
MediHelp rates the interaction as moderate. Anthrax vaccine adsorbed and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxaliplatin chemotherapy suppresses the immune system and may reduce antibody response to the anthrax vaccine. Protection may be incomplete if vaccination occurs during or soon before treatment.
How serious is the interaction between Anthrax vaccine adsorbed and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate at least 2 weeks before starting chemotherapy when possible. If given during treatment, revaccinate about 3 months after chemotherapy is completed.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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