Drug interactions
Anthrax vaccine + Anti-thymocyte
Severity: Moderate
Anthrax vaccine and Anti-thymocyte: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anti-thymocyte globulin profoundly depletes T cells and can blunt the immune response to vaccination. Protection from the vaccine may be inadequate if given during or shortly after treatment. Anthrax vaccine is non-live, so the concern is reduced efficacy rather than infection.
What this interaction means in plain words
Anthrax vaccine and Anti-thymocyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
T-lymphocyte depletion by anti-thymocyte globulin impairs the immune response to the vaccine antigen.
What to do
Where possible, vaccinate before starting immunosuppression or defer until immune recovery. If given during therapy, consider checking antibody response and revaccinating later.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anthrax vaccine and Anti-thymocyte, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicated
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicated
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicated
- Anti-thymocyte + Measles vaccine Contraindicated
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Anthrax vaccine with Anti-thymocyte?
MediHelp rates the interaction as moderate. Anthrax vaccine and Anti-thymocyte can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anti-thymocyte globulin profoundly depletes T cells and can blunt the immune response to vaccination. Protection from the vaccine may be inadequate if given during or shortly after treatment. Anthrax vaccine is non-live, so the concern is reduced efficacy rather than infection.
How serious is the interaction between Anthrax vaccine and Anti-thymocyte?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, vaccinate before starting immunosuppression or defer until immune recovery. If given during therapy, consider checking antibody response and revaccinating later.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
