Drug interactions
Anti-thymocyte + Astragalus
Severity: Moderate
Anti-thymocyte and Astragalus: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Astragalus is claimed to stimulate immune function and might oppose the immunosuppression from anti-thymocyte globulin. This could theoretically raise the risk of rejection or reduce the effect of induction therapy.
What this interaction means in plain words
Anti-thymocyte and Astragalus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible immunostimulatory activity of astragalus opposing T-cell depletion; evidence is not well established.
What to do
Advise transplant patients to avoid astragalus during and after antithymocyte globulin therapy. Monitor graft function if it has been used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicated
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicated
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicated
- Anti-thymocyte + Measles vaccine Contraindicated
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Anti-thymocyte with Astragalus?
MediHelp rates the interaction as moderate. Anti-thymocyte and Astragalus can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Astragalus is claimed to stimulate immune function and might oppose the immunosuppression from anti-thymocyte globulin. This could theoretically raise the risk of rejection or reduce the effect of induction therapy.
How serious is the interaction between Anti-thymocyte and Astragalus?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant patients to avoid astragalus during and after antithymocyte globulin therapy. Monitor graft function if it has been used.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
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