Drug interactions
Anti-thymocyte + Influenza virus vaccine quadrivalent recombinant
Severity: Moderate
Anti-thymocyte and Influenza virus vaccine quadrivalent recombinant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anti-thymocyte globulin depletes T cells and can weaken the antibody response to inactivated or recombinant influenza vaccines. The vaccine is not harmful, but protection may be inadequate.
What this interaction means in plain words
Anti-thymocyte and Influenza virus vaccine quadrivalent recombinant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
T-cell depletion reduces immunogenicity of the vaccine.
What to do
Vaccinate when clinically indicated and do not withhold annual influenza immunization, though ideally before therapy. Consider household vaccination and early antiviral treatment if exposed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anti-thymocyte and Influenza virus vaccine quadrivalent recombinant, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicated
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicated
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicated
- Anti-thymocyte + Measles vaccine Contraindicated
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Anti-thymocyte with Influenza virus vaccine quadrivalent recombinant?
MediHelp rates the interaction as moderate. Anti-thymocyte and Influenza virus vaccine quadrivalent recombinant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anti-thymocyte globulin depletes T cells and can weaken the antibody response to inactivated or recombinant influenza vaccines. The vaccine is not harmful, but protection may be inadequate.
How serious is the interaction between Anti-thymocyte and Influenza virus vaccine quadrivalent recombinant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate when clinically indicated and do not withhold annual influenza immunization, though ideally before therapy. Consider household vaccination and early antiviral treatment if exposed.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
