Drug interactions
Anti-thymocyte + Japanese encephalitis virus vaccine
Severity: Moderate
Anti-thymocyte and Japanese encephalitis virus vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anti-thymocyte globulin may reduce the immune response to Japanese encephalitis vaccine. This matters for patients traveling to endemic regions who may think they are protected.
What this interaction means in plain words
Anti-thymocyte and Japanese encephalitis virus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism: T-cell depletion impairs the response to the vaccine.
What to do
Complete vaccination before immunosuppression if possible, or defer until immune recovery. Advise strict mosquito-avoidance measures and consider checking antibody titers.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicated
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicated
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicated
- Anti-thymocyte + Measles vaccine Contraindicated
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Anti-thymocyte with Japanese encephalitis virus vaccine?
MediHelp rates the interaction as moderate. Anti-thymocyte and Japanese encephalitis virus vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anti-thymocyte globulin may reduce the immune response to Japanese encephalitis vaccine. This matters for patients traveling to endemic regions who may think they are protected.
How serious is the interaction between Anti-thymocyte and Japanese encephalitis virus vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete vaccination before immunosuppression if possible, or defer until immune recovery. Advise strict mosquito-avoidance measures and consider checking antibody titers.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
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