Drug interactions
Anti-thymocyte + Meningococcal a c y and w-135 polysaccharide vaccine combined
Severity: Moderate
Anti-thymocyte and Meningococcal a c y and w-135 polysaccharide vaccine combined: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anti-thymocyte globulin may reduce the antibody response to meningococcal polysaccharide vaccine. Protection against invasive disease may be inadequate.
What this interaction means in plain words
Anti-thymocyte and Meningococcal a c y and w-135 polysaccharide vaccine combined can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism: lymphocyte depletion impairs vaccine-induced antibody production.
What to do
Vaccinate before immunosuppression where possible, or defer until immune recovery. Follow recommendations for booster doses in immunocompromised patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anti-thymocyte and Meningococcal a c y and w-135 polysaccharide vaccine combined, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Contraindicated
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Anti-thymocyte + Measles mumps and rubella vaccine live Contraindicated
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Contraindicated
- Anti-thymocyte + Measles vaccine Contraindicated
- Anti-thymocyte + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Anti-thymocyte with Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates the interaction as moderate. Anti-thymocyte and Meningococcal a c y and w-135 polysaccharide vaccine combined can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anti-thymocyte globulin may reduce the antibody response to meningococcal polysaccharide vaccine. Protection against invasive disease may be inadequate.
How serious is the interaction between Anti-thymocyte and Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before immunosuppression where possible, or defer until immune recovery. Follow recommendations for booster doses in immunocompromised patients.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
