Drug interactions
Arformoterol + Clarithromycin
Severity: Moderate
Arformoterol and Clarithromycin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Clarithromycin prolongs the QT interval and beta-agonists such as arformoterol may add to this and lower potassium. The risk is mostly relevant in patients with other arrhythmia risk factors.
What this interaction means in plain words
Arformoterol and Clarithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Clarithromycin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation and beta-agonist-induced hypokalemia.
What to do
Monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Consider a non-macrolide antibiotic in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Clarithromycin
- Astemizole + Clarithromycin Contraindicated
- Avanafil + Clarithromycin Contraindicated
- Cisapride + Clarithromycin Contraindicated
- Clarithromycin + Colchicine Contraindicated
- Clarithromycin + Conivaptan Contraindicated
- Clarithromycin + Dihydroergotamine Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Clarithromycin?
MediHelp rates the interaction as moderate. Arformoterol and Clarithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Clarithromycin prolongs the QT interval and beta-agonists such as arformoterol may add to this and lower potassium. The risk is mostly relevant in patients with other arrhythmia risk factors.
How serious is the interaction between Arformoterol and Clarithromycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with cardiac disease or other QT-prolonging drugs. Consider a non-macrolide antibiotic in high-risk patients.
What other medicines interact with Clarithromycin?
MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.
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