Drug interactions
Arformoterol + Gemifloxacin
Severity: Moderate
Arformoterol and Gemifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gemifloxacin prolongs the QT interval, and arformoterol, a long-acting beta-agonist, can lower potassium and increase heart rate. Together they may raise the risk of ventricular arrhythmia.
What this interaction means in plain words
Arformoterol and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Gemifloxacin belongs to Anti Bacterial.
Why it happens
Gemifloxacin blocks repolarizing potassium channels, while beta-agonist-induced hypokalemia and tachycardia add to QT-related arrhythmia risk.
What to do
Monitor ECG and serum potassium, especially in patients with cardiac disease. Correct any electrolyte deficits and avoid other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Gemifloxacin?
MediHelp rates the interaction as moderate. Arformoterol and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gemifloxacin prolongs the QT interval, and arformoterol, a long-acting beta-agonist, can lower potassium and increase heart rate. Together they may raise the risk of ventricular arrhythmia.
How serious is the interaction between Arformoterol and Gemifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium, especially in patients with cardiac disease. Correct any electrolyte deficits and avoid other QT-prolonging drugs.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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