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Drug interactions

Arformoterol + Gentamicin

Severity: Moderate

Arformoterol and Gentamicin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Arformoterol, a long-acting beta-2 agonist, lowers serum potassium by cellular uptake, and gentamicin may cause renal potassium and magnesium loss. The combination can cause additive hypokalemia with a risk of arrhythmias.

What this interaction means in plain words

Arformoterol and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Arformoterol belongs to Respiratory; Gentamicin belongs to Anti Bacterial.

Evidence level: Moderate

Why it happens

Beta-2 agonist-induced intracellular potassium shift plus aminoglycoside-related renal electrolyte wasting.

What to do

Check potassium and magnesium at baseline and periodically during combined use, and correct abnormalities promptly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Arformoterol with Gentamicin?

MediHelp rates the interaction as moderate. Arformoterol and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta-2 agonist, lowers serum potassium by cellular uptake, and gentamicin may cause renal potassium and magnesium loss. The combination can cause additive hypokalemia with a risk of arrhythmias.

How serious is the interaction between Arformoterol and Gentamicin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium at baseline and periodically during combined use, and correct abnormalities promptly.

What other medicines interact with Gentamicin?

MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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