Drug interactions
Arformoterol + Haloperidol
Severity: Moderate
Arformoterol and Haloperidol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both haloperidol and long-acting beta-2 agonists such as arformoterol can prolong the QT interval, and beta-agonists may lower serum potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with heart disease or electrolyte abnormalities.
What this interaction means in plain words
Arformoterol and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Haloperidol belongs to Central Nervous System.
Why it happens
Additive QT prolongation with beta-agonist-related hypokalemia.
What to do
Obtain a baseline ECG and check potassium and magnesium in patients with cardiac risk factors, and repeat if doses change. Correct electrolyte abnormalities before and during combined use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Haloperidol?
MediHelp rates the interaction as moderate. Arformoterol and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both haloperidol and long-acting beta-2 agonists such as arformoterol can prolong the QT interval, and beta-agonists may lower serum potassium. Together they may increase the risk of ventricular arrhythmias, particularly in patients with heart disease or electrolyte abnormalities.
How serious is the interaction between Arformoterol and Haloperidol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and check potassium and magnesium in patients with cardiac risk factors, and repeat if doses change. Correct electrolyte abnormalities before and during combined use.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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