Drug interactions
Arformoterol + Moxifloxacin
Severity: Moderate
Arformoterol and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin prolongs the QT interval and arformoterol, a long-acting beta-2 agonist, can cause hypokalemia, tachycardia and QT prolongation. The combination may increase the risk of ventricular arrhythmia, especially in patients with heart disease.
What this interaction means in plain words
Arformoterol and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia adding to arrhythmic risk.
What to do
Check ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use an alternative antibiotic if the QTc is significantly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Moxifloxacin?
MediHelp rates the interaction as moderate. Arformoterol and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxifloxacin prolongs the QT interval and arformoterol, a long-acting beta-2 agonist, can cause hypokalemia, tachycardia and QT prolongation. The combination may increase the risk of ventricular arrhythmia, especially in patients with heart disease.
How serious is the interaction between Arformoterol and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use an alternative antibiotic if the QTc is significantly prolonged.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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