Drug interactions
Aripiprazole + Scopolamine
Severity: Minor
Aripiprazole and Scopolamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aripiprazole has little intrinsic anticholinergic activity, but combined use with scopolamine may increase sedation, confusion and anticholinergic effects. Clinically significant interference with absorption or efficacy is not well established.
What this interaction means in plain words
Aripiprazole and Scopolamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Scopolamine belongs to Respiratory.
Why it happens
Mainly additive central effects of scopolamine; no firmly established pharmacokinetic mechanism.
What to do
Monitor for sedation and confusion, especially in older adults. No dose adjustment is usually required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Scopolamine
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Scopolamine?
MediHelp rates the interaction as minor. Aripiprazole and Scopolamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aripiprazole has little intrinsic anticholinergic activity, but combined use with scopolamine may increase sedation, confusion and anticholinergic effects. Clinically significant interference with absorption or efficacy is not well established.
How serious is the interaction between Aripiprazole and Scopolamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and confusion, especially in older adults. No dose adjustment is usually required.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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