Drug interactions
Asenapine transdermal + Flibanserin
Severity: Moderate
Asenapine transdermal and Flibanserin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs cause CNS depression, so combined use may increase sedation, dizziness and impaired alertness. Flibanserin can also cause hypotension and syncope.
What this interaction means in plain words
Asenapine transdermal and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depressant effects.
What to do
Counsel on drowsiness and avoiding driving, and monitor for sedation and hypotension, reducing doses if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Frequently asked questions
Can I take Asenapine transdermal with Flibanserin?
MediHelp rates the interaction as moderate. Asenapine transdermal and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause CNS depression, so combined use may increase sedation, dizziness and impaired alertness. Flibanserin can also cause hypotension and syncope.
How serious is the interaction between Asenapine transdermal and Flibanserin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on drowsiness and avoiding driving, and monitor for sedation and hypotension, reducing doses if needed.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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