Drug interactions
Atazanavir + Cabergoline
Severity: Moderate
Atazanavir and Cabergoline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atazanavir is a strong CYP3A4 inhibitor and boosted regimens increase this effect. Cabergoline levels may rise, increasing dopaminergic adverse effects such as nausea, orthostatic hypotension and somnolence.
What this interaction means in plain words
Atazanavir and Cabergoline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atazanavir belongs to Anti Virals; Cabergoline belongs to Endocrine.
Why it happens
Inhibition of CYP3A4-mediated cabergoline metabolism.
What to do
Start with a low cabergoline dose, titrate slowly and monitor blood pressure and tolerability. Consider an alternative if adverse effects occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cabergoline
- Cabergoline + Promethazine Contraindicated
- Benperidol + Cabergoline Major
- Cabergoline + Chlorpromazine Major
- Cabergoline + Clarithromycin Major
- Cabergoline + Dexfenfluramine Major
- Cabergoline + Droperidol Major
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Cabergoline?
MediHelp rates the interaction as moderate. Atazanavir and Cabergoline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atazanavir is a strong CYP3A4 inhibitor and boosted regimens increase this effect. Cabergoline levels may rise, increasing dopaminergic adverse effects such as nausea, orthostatic hypotension and somnolence.
How serious is the interaction between Atazanavir and Cabergoline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with a low cabergoline dose, titrate slowly and monitor blood pressure and tolerability. Consider an alternative if adverse effects occur.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Promethazine, Benperidol, Chlorpromazine. The full list is on the Cabergoline page.
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