Drug interactions
Atazanavir + Galantamine
Severity: Minor
Atazanavir and Galantamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atazanavir inhibits CYP3A4, one of the two main enzymes that clear galantamine, so galantamine exposure may rise modestly. This could increase cholinergic effects such as nausea, vomiting, bradycardia and dizziness.
What this interaction means in plain words
Atazanavir and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Galantamine belongs to Central Nervous System.
Why it happens
Inhibition of CYP3A4-mediated galantamine metabolism by atazanavir.
What to do
No routine dose change is needed; titrate galantamine according to tolerability and monitor heart rate and gastrointestinal symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Galantamine?
MediHelp rates the interaction as minor. Atazanavir and Galantamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atazanavir inhibits CYP3A4, one of the two main enzymes that clear galantamine, so galantamine exposure may rise modestly. This could increase cholinergic effects such as nausea, vomiting, bradycardia and dizziness.
How serious is the interaction between Atazanavir and Galantamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; titrate galantamine according to tolerability and monitor heart rate and gastrointestinal symptoms.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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