Drug interactions
Atazanavir + Glipizide-metformin
Severity: Minor
Atazanavir and Glipizide-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Protease inhibitors are associated with insulin resistance and hyperglycemia, which may reduce glycemic control on glipizide and metformin. Atazanavir has a comparatively lower metabolic effect than other protease inhibitors.
What this interaction means in plain words
Atazanavir and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Glipizide-metformin belongs to Endocrine.
Why it happens
Protease inhibitor associated insulin resistance and impaired glucose metabolism.
What to do
Monitor blood glucose and HbA1c and adjust antidiabetic therapy as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glipizide-metformin
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Glipizide-metformin?
MediHelp rates the interaction as minor. Atazanavir and Glipizide-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Protease inhibitors are associated with insulin resistance and hyperglycemia, which may reduce glycemic control on glipizide and metformin. Atazanavir has a comparatively lower metabolic effect than other protease inhibitors.
How serious is the interaction between Atazanavir and Glipizide-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c and adjust antidiabetic therapy as needed.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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