Drug interactions
Atenolol + Clevidipine
Severity: Moderate
Atenolol and Clevidipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so combined use gives additive hypotension. Beta blockade may also blunt the reflex tachycardia from clevidipine and add negative inotropic effect in impaired ventricular function.
What this interaction means in plain words
Atenolol and Clevidipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Clevidipine belongs to Cardiovascular.
Why it happens
Additive vasodilation from calcium channel blockade and reduced cardiac output from beta blockade.
What to do
Titrate clevidipine with continuous blood pressure and heart rate monitoring and reduce doses if hypotension or bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Other interactions of Clevidipine
Frequently asked questions
Can I take Atenolol with Clevidipine?
MediHelp rates the interaction as moderate. Atenolol and Clevidipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so combined use gives additive hypotension. Beta blockade may also blunt the reflex tachycardia from clevidipine and add negative inotropic effect in impaired ventricular function.
How serious is the interaction between Atenolol and Clevidipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate clevidipine with continuous blood pressure and heart rate monitoring and reduce doses if hypotension or bradycardia occurs.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
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