Drug interactions
Atenolol + Indacaterol-glycopyrronium
Severity: Moderate
Atenolol and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atenolol is cardioselective but can still blunt the bronchodilator effect of indacaterol, particularly at higher doses or in patients with reactive airways. Bronchospasm is possible in asthma.
What this interaction means in plain words
Atenolol and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism at beta receptors, with partial loss of selectivity at higher doses.
What to do
If a beta-blocker is needed, use the lowest effective dose of a cardioselective agent and monitor lung function and symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Atenolol and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atenolol is cardioselective but can still blunt the bronchodilator effect of indacaterol, particularly at higher doses or in patients with reactive airways. Bronchospasm is possible in asthma.
How serious is the interaction between Atenolol and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If a beta-blocker is needed, use the lowest effective dose of a cardioselective agent and monitor lung function and symptoms.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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