Drug interactions
Amisulpride + Indacaterol-glycopyrronium
Severity: Major
Amisulpride and Indacaterol-glycopyrronium: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amisulpride causes dose-related QT prolongation, and indacaterol can add to arrhythmia risk through hypokalemia and tachycardia.
What this interaction means in plain words
Amisulpride and Indacaterol-glycopyrronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-2 agonist induced hypokalemia.
What to do
Obtain ECG and correct electrolytes; monitor QTc during coadministration or choose an alternative.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Amisulpride
- Amiodarone + Amisulpride Contraindicated
- Amisulpride + Arsenic trioxide Contraindicated
- Amisulpride + Disopyramide Contraindicated
- Amisulpride + Dofetilide Contraindicated
- Amisulpride + Droperidol Contraindicated
- Amisulpride + Ibutilide Contraindicated
Frequently asked questions
Can I take Amisulpride with Indacaterol-glycopyrronium?
MediHelp rates the interaction as major. Amisulpride and Indacaterol-glycopyrronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride causes dose-related QT prolongation, and indacaterol can add to arrhythmia risk through hypokalemia and tachycardia.
How serious is the interaction between Amisulpride and Indacaterol-glycopyrronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain ECG and correct electrolytes; monitor QTc during coadministration or choose an alternative.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Arformoterol, Arsenic trioxide, Betaxolol. The full list is on the Indacaterol-glycopyrronium page.
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