Drug interactions
Atomoxetine + Dasatinib
Severity: Moderate
Atomoxetine and Dasatinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is associated with QT prolongation, and atomoxetine has potential QT and heart rate effects. Using them together may add to the risk of arrhythmia, especially with electrolyte disturbance or heart disease.
What this interaction means in plain words
Atomoxetine and Dasatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Dasatinib belongs to Oncology.
Why it happens
Additive QT prolongation (pharmacodynamic).
What to do
Check ECG at baseline and periodically, and correct hypokalemia and hypomagnesemia. Avoid adding other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Atomoxetine with Dasatinib?
MediHelp rates the interaction as moderate. Atomoxetine and Dasatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib is associated with QT prolongation, and atomoxetine has potential QT and heart rate effects. Using them together may add to the risk of arrhythmia, especially with electrolyte disturbance or heart disease.
How serious is the interaction between Atomoxetine and Dasatinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG at baseline and periodically, and correct hypokalemia and hypomagnesemia. Avoid adding other QT-prolonging drugs.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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