Drug interactions
Atomoxetine + Gemifloxacin
Severity: Moderate
Atomoxetine and Gemifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs may prolong the QT interval, and combined use may increase the risk of arrhythmia, particularly in patients with underlying cardiac disease or electrolyte abnormalities. Atomoxetine's QT effect is modest.
What this interaction means in plain words
Atomoxetine and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Gemifloxacin belongs to Anti Bacterial.
Why it happens
Additive prolongation of ventricular repolarization.
What to do
Avoid the combination in patients with known QT prolongation or cardiac risk. Otherwise check ECG and electrolytes and monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gemifloxacin
- Arsenic trioxide + Gemifloxacin Contraindicated
- Dofetilide + Gemifloxacin Contraindicated
- Gemifloxacin + Ibutilide Contraindicated
- Gemifloxacin + Pimozide Contraindicated
- Gemifloxacin + Thioridazine Contraindicated
- Gemifloxacin + Vandetanib Contraindicated
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Gemifloxacin?
MediHelp rates the interaction as moderate. Atomoxetine and Gemifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs may prolong the QT interval, and combined use may increase the risk of arrhythmia, particularly in patients with underlying cardiac disease or electrolyte abnormalities. Atomoxetine's QT effect is modest.
How serious is the interaction between Atomoxetine and Gemifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in patients with known QT prolongation or cardiac risk. Otherwise check ECG and electrolytes and monitor for palpitations or syncope.
What other medicines interact with Gemifloxacin?
MediHelp also lists interactions of Gemifloxacin with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Gemifloxacin page.
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