Drug interactions
Atomoxetine + Lurasidone
Severity: Minor
Atomoxetine and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents act on the central nervous system, and combined use may lead to more somnolence, dizziness or other adverse effects. Atomoxetine can also raise heart rate and blood pressure, which may complicate treatment with an antipsychotic.
What this interaction means in plain words
Atomoxetine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atomoxetine belongs to Central Nervous System; Lurasidone belongs to Central Nervous System.
Why it happens
Additive central nervous system effects; no well-established pharmacokinetic interaction.
What to do
Monitor for sedation, dizziness and changes in blood pressure and heart rate when starting or adjusting either drug. No dose change is routinely needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Atomoxetine with Lurasidone?
MediHelp rates the interaction as minor. Atomoxetine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents act on the central nervous system, and combined use may lead to more somnolence, dizziness or other adverse effects. Atomoxetine can also raise heart rate and blood pressure, which may complicate treatment with an antipsychotic.
How serious is the interaction between Atomoxetine and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation, dizziness and changes in blood pressure and heart rate when starting or adjusting either drug. No dose change is routinely needed.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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