Drug reference
lurasidone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Atypical antipsychotic; precise mechanism is unknown; efficacy suggested to involve mediation of central dopamine type 2 and serotonin type 2 (5HT-2A) receptor antagonism
Common side effects
- Insomnia
- Somnolence
- Nausea
- Akathisia
- Parkinsonism
- Extrapyramidal disorder
- Fasting glucose increased
Known interactions (17)
- carbamazepine + lurasidone Contraindicated
- clarithromycin + lurasidone Contraindicated
- enzalutamide + lurasidone Contraindicated
- itraconazole + lurasidone Contraindicated
- ketoconazole + lurasidone Contraindicated
- lurasidone + rifampin Contraindicated
- lurasidone + ritonavir Contraindicated
- amisulpride + lurasidone Major
- amobarbital + lurasidone Major
- adrenaline-articaine + lurasidone Moderate
- chloramphenicol + lurasidone Moderate
- dexamethasone + lurasidone Moderate
- dopamine + lurasidone Moderate
- epinephrine + lurasidone Moderate
- eslicarbazepine + lurasidone Moderate
- imatinib + lurasidone Moderate
- isoniazid + lurasidone Moderate
Related conditions
Frequently asked questions
What drug class is lurasidone?
lurasidone belongs to: Central Nervous System.
How does lurasidone work?
Atypical antipsychotic; precise mechanism is unknown; efficacy suggested to involve mediation of central dopamine type 2 and serotonin type 2 (5HT-2A) receptor antagonism
What are the common side effects of lurasidone?
Insomnia, Somnolence, Nausea, Akathisia, Parkinsonism, Extrapyramidal disorder, Fasting glucose increased
Which drugs interact with lurasidone?
carbamazepine, clarithromycin, enzalutamide, itraconazole, ketoconazole, rifampin, ritonavir, amisulpride, amobarbital, adrenaline-articaine, chloramphenicol, dexamethasone, dopamine, epinephrine, eslicarbazepine
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