Drug interactions
Atorvastatin + Bosutinib
Severity: Minor
Atorvastatin and Bosutinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin may weakly inhibit P-glycoprotein and slightly increase bosutinib exposure. The effect is expected to be small.
What this interaction means in plain words
Atorvastatin and Bosutinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Bosutinib belongs to Oncology.
Why it happens
Possible weak P-glycoprotein inhibition by atorvastatin decreasing bosutinib efflux.
What to do
No dose change is usually needed; monitor for bosutinib gastrointestinal and hepatic adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Other interactions of Bosutinib
- Amiodarone + Bosutinib Major
- Apalutamide + Bosutinib Major
- Aprepitant + Bosutinib Major
- Bosentan + Bosutinib Major
- Bosutinib + Carbamazepine Major
- Bosutinib + Chlorpromazine Major
Frequently asked questions
Can I take Atorvastatin with Bosutinib?
MediHelp rates the interaction as minor. Atorvastatin and Bosutinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin may weakly inhibit P-glycoprotein and slightly increase bosutinib exposure. The effect is expected to be small.
How serious is the interaction between Atorvastatin and Bosutinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for bosutinib gastrointestinal and hepatic adverse effects.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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