Drug interactions
Axitinib + Famotidine
Severity: Minor
Axitinib and Famotidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Axitinib solubility falls as gastric pH rises, so acid suppression could reduce its absorption slightly. Labeling suggests the effect is not clinically significant.
What this interaction means in plain words
Axitinib and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Axitinib belongs to Oncology; Famotidine belongs to Gastrointestinal Tract.
Why it happens
Increased gastric pH may reduce axitinib dissolution and absorption.
What to do
No dose change is required; monitor treatment response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Famotidine
Other interactions of Axitinib
- Amobarbital + Axitinib Major
- Apalutamide + Axitinib Major
- Atazanavir + Axitinib Major
- Axitinib + Carbamazepine Major
- Axitinib + Clarithromycin Major
- Axitinib + Cobicistat Major
Frequently asked questions
Can I take Axitinib with Famotidine?
MediHelp rates the interaction as minor. Axitinib and Famotidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Axitinib solubility falls as gastric pH rises, so acid suppression could reduce its absorption slightly. Labeling suggests the effect is not clinically significant.
How serious is the interaction between Axitinib and Famotidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required; monitor treatment response.
What other medicines interact with Famotidine?
MediHelp also lists interactions of Famotidine with, for example, Atazanavir, Dasatinib, Infigratinib. The full list is on the Famotidine page.
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