Drug interactions
Azelastine + Etomidate
Severity: Moderate
Azelastine and Etomidate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etomidate is a hypnotic anesthetic, and azelastine can cause drowsiness. Together they may deepen or prolong sedation, mainly relevant if systemic azelastine exposure is meaningful.
What this interaction means in plain words
Azelastine and Etomidate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine belongs to Respiratory; Etomidate belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects (pharmacodynamic synergism).
What to do
Inform the anesthesia team of recent azelastine use. Titrate etomidate to effect and monitor sedation depth and recovery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azelastine
Other interactions of Etomidate
- Alprazolam + Etomidate Moderate
- Amitriptyline + Etomidate Moderate
- Amobarbital + Etomidate Moderate
- Baclofen + Etomidate Moderate
- Brompheniramine + Etomidate Moderate
- Buprenorphine + Etomidate Moderate
Frequently asked questions
Can I take Azelastine with Etomidate?
MediHelp rates the interaction as moderate. Azelastine and Etomidate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Etomidate is a hypnotic anesthetic, and azelastine can cause drowsiness. Together they may deepen or prolong sedation, mainly relevant if systemic azelastine exposure is meaningful.
How serious is the interaction between Azelastine and Etomidate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inform the anesthesia team of recent azelastine use. Titrate etomidate to effect and monitor sedation depth and recovery.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
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