Drug interactions
Azficel-t + Fondaparinux
Severity: Moderate
Azficel-t and Fondaparinux: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is injected intradermally after a skin biopsy, and anticoagulants may increase bruising and bleeding at these sites. Labeling advises against concurrent use.
What this interaction means in plain words
Azficel-t and Fondaparinux can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anticoagulant-related impairment of hemostasis at biopsy and injection sites.
What to do
Have the prescriber decide whether fondaparinux can be interrupted around biopsy and injection sessions. Monitor sites for bruising and bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Azficel-t with Fondaparinux?
MediHelp rates the interaction as moderate. Azficel-t and Fondaparinux can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is injected intradermally after a skin biopsy, and anticoagulants may increase bruising and bleeding at these sites. Labeling advises against concurrent use.
How serious is the interaction between Azficel-t and Fondaparinux?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Have the prescriber decide whether fondaparinux can be interrupted around biopsy and injection sessions. Monitor sites for bruising and bleeding.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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