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Drug interactions

Azficel-t + Mefenamic acid

Severity: Moderate

Azficel-t and Mefenamic acid: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

NSAIDs can increase bruising and bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.

What this interaction means in plain words

Azficel-t and Mefenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

NSAID-mediated reversible inhibition of platelet aggregation increases local bleeding and bruising.

What to do

Hold mefenamic acid before and after the biopsy and injection procedures as directed by the product labeling, and use an alternative analgesic if needed.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Azficel-t with Mefenamic acid?

MediHelp rates the interaction as moderate. Azficel-t and Mefenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. NSAIDs can increase bruising and bleeding at the biopsy and injection sites used for azficel-T treatment. The product labeling advises against concomitant NSAID use around these procedures.

How serious is the interaction between Azficel-t and Mefenamic acid?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Hold mefenamic acid before and after the biopsy and injection procedures as directed by the product labeling, and use an alternative analgesic if needed.

What other medicines interact with Mefenamic acid?

MediHelp also lists interactions of Mefenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Mefenamic acid page.

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