Drug interactions
Azficel-t + Rivaroxaban
Severity: Moderate
Azficel-t and Rivaroxaban: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is delivered by multiple intradermal injections after a skin biopsy. Anticoagulants such as rivaroxaban can increase bruising and bleeding at the biopsy and injection sites.
What this interaction means in plain words
Azficel-t and Rivaroxaban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic effect: anticoagulation increases bleeding and bruising at procedural sites.
What to do
Have the prescriber decide whether to hold rivaroxaban around the biopsy and injection procedures, balancing thrombotic risk. Monitor the sites for bleeding and hematoma.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Azficel-t and Rivaroxaban, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Rivaroxaban
- Defibrotide + Rivaroxaban Contraindicated
- Ketoconazole + Rivaroxaban Contraindicated
- Ketorolac + Rivaroxaban Contraindicated
- Abciximab + Rivaroxaban Major
- Acalabrutinib + Rivaroxaban Major
- Acetylsalicylic acid + Rivaroxaban Major
Frequently asked questions
Can I take Azficel-t with Rivaroxaban?
MediHelp rates the interaction as moderate. Azficel-t and Rivaroxaban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is delivered by multiple intradermal injections after a skin biopsy. Anticoagulants such as rivaroxaban can increase bruising and bleeding at the biopsy and injection sites.
How serious is the interaction between Azficel-t and Rivaroxaban?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Have the prescriber decide whether to hold rivaroxaban around the biopsy and injection procedures, balancing thrombotic risk. Monitor the sites for bleeding and hematoma.
What other medicines interact with Rivaroxaban?
MediHelp also lists interactions of Rivaroxaban with, for example, Defibrotide, Ketoconazole, Ketorolac. The full list is on the Rivaroxaban page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
