Drug interactions
Azilsartan + Insulin degludec-liraglutide
Severity: Minor
Azilsartan and Insulin degludec-liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and modestly enhance the glucose-lowering effect of insulin and other antidiabetic drugs. Hypoglycemia is possible, particularly when azilsartan is started.
What this interaction means in plain words
Azilsartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan belongs to Cardiovascular; Insulin degludec-liraglutide belongs to Endocrine.
Why it happens
Improved insulin sensitivity from angiotensin II receptor blockade adds to the glucose-lowering action of insulin and liraglutide.
What to do
Monitor blood glucose when azilsartan is started or stopped, and lower the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Frequently asked questions
Can I take Azilsartan with Insulin degludec-liraglutide?
MediHelp rates the interaction as minor. Azilsartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and modestly enhance the glucose-lowering effect of insulin and other antidiabetic drugs. Hypoglycemia is possible, particularly when azilsartan is started.
How serious is the interaction between Azilsartan and Insulin degludec-liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when azilsartan is started or stopped, and lower the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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