Drug interactions
Azilsartan + Insulin degludec
Severity: Minor
Azilsartan and Insulin degludec: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose lowering effect of insulin. This may increase the risk of hypoglycemia, mainly after starting or increasing the ARB.
What this interaction means in plain words
Azilsartan and Insulin degludec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan belongs to Cardiovascular; Insulin degludec belongs to Endocrine.
Why it happens
Angiotensin receptor blockade may improve insulin sensitivity, adding to the glucose lowering effect of insulin.
What to do
Monitor blood glucose when azilsartan is started or its dose changed, and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azilsartan
- Aliskiren + Azilsartan Contraindicated
- Azilsartan + Sparsentan Contraindicated
- Amifostine + Azilsartan Major
- Amlodipine-benazepril + Azilsartan Major
- Amlodipine-perindopril + Azilsartan Major
- Azilsartan + Benazepril Major
Other interactions of Insulin degludec
Frequently asked questions
Can I take Azilsartan with Insulin degludec?
MediHelp rates the interaction as minor. Azilsartan and Insulin degludec have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and can enhance the glucose lowering effect of insulin. This may increase the risk of hypoglycemia, mainly after starting or increasing the ARB.
How serious is the interaction between Azilsartan and Insulin degludec?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when azilsartan is started or its dose changed, and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Azilsartan?
MediHelp also lists interactions of Azilsartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Azilsartan page.
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