Drug interactions
Azilsartan-chlorthalidone + Cefadroxil
Severity: Minor
Azilsartan-chlorthalidone and Cefadroxil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefadroxil is renally eliminated by tubular secretion and may compete with chlorthalidone, though the clinical effect is small. Both drugs' levels could rise modestly in renal impairment.
What this interaction means in plain words
Azilsartan-chlorthalidone and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azilsartan-chlorthalidone belongs to Cardiovascular; Cefadroxil belongs to Anti Bacterial.
Why it happens
Possible competition for renal tubular secretion by organic anion transporters.
What to do
No routine change is needed; adjust cefadroxil dosing to renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Azilsartan-chlorthalidone and Cefadroxil, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Azilsartan-chlorthalidone
Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Azilsartan-chlorthalidone with Cefadroxil?
MediHelp rates the interaction as minor. Azilsartan-chlorthalidone and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefadroxil is renally eliminated by tubular secretion and may compete with chlorthalidone, though the clinical effect is small. Both drugs' levels could rise modestly in renal impairment.
How serious is the interaction between Azilsartan-chlorthalidone and Cefadroxil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; adjust cefadroxil dosing to renal function.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
