Drug interactions
Azithromycin + Biotin
Severity: Minor
Azithromycin and Biotin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The suggested effect is reduced biotin availability from altered gut flora, but the clinical relevance is negligible. Biotin deficiency from short antibiotic courses is not an established concern.
What this interaction means in plain words
Azithromycin and Biotin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azithromycin belongs to Anti Bacterial; Biotin belongs to Gastrointestinal Tract.
Why it happens
Theoretical reduction of biotin-producing intestinal bacteria; not established clinically.
What to do
No action is required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Other interactions of Biotin
- Biotin + Levothyroxine Moderate
- Biotin + Carbamazepine Minor
- Biotin + Cefalexin Minor
- Biotin + Erythromycin base Minor
- Biotin + Erythromycin ethylsuccinate Minor
- Biotin + Erythromycin stearate Minor
Frequently asked questions
Can I take Azithromycin with Biotin?
MediHelp rates the interaction as minor. Azithromycin and Biotin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The suggested effect is reduced biotin availability from altered gut flora, but the clinical relevance is negligible. Biotin deficiency from short antibiotic courses is not an established concern.
How serious is the interaction between Azithromycin and Biotin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is required.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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