Drug interactions
Biotin + Carbamazepine
Severity: Minor
Biotin and Carbamazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Long-term carbamazepine use has been associated with lower biotin levels. Clinical deficiency is uncommon.
What this interaction means in plain words
Biotin and Carbamazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Biotin belongs to Gastrointestinal Tract; Carbamazepine belongs to Central Nervous System.
Why it happens
Proposed reduced absorption or increased catabolism of biotin; the mechanism is not established.
What to do
Routine supplementation is not required. Consider biotin if signs of deficiency develop during long-term therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicated
- Cabotegravir + Carbamazepine Contraindicated
- Carbamazepine + Delamanid Contraindicated
- Carbamazepine + Dienogest / estradiol valerate Contraindicated
- Carbamazepine + Doravirine Contraindicated
- Carbamazepine + Elbasvir / grazoprevir Contraindicated
Other interactions of Biotin
- Biotin + Levothyroxine Moderate
- Azithromycin + Biotin Minor
- Biotin + Cefalexin Minor
- Biotin + Erythromycin base Minor
- Biotin + Erythromycin ethylsuccinate Minor
- Biotin + Erythromycin stearate Minor
Frequently asked questions
Can I take Biotin with Carbamazepine?
MediHelp rates the interaction as minor. Biotin and Carbamazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Long-term carbamazepine use has been associated with lower biotin levels. Clinical deficiency is uncommon.
How serious is the interaction between Biotin and Carbamazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Routine supplementation is not required. Consider biotin if signs of deficiency develop during long-term therapy.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
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