Drug interactions
Azithromycin + Telavancin
Severity: Moderate
Azithromycin and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azithromycin can prolong the QTc interval and has been associated with torsades de pointes. With telavancin, the combined effect on repolarization may increase arrhythmia risk, especially with other risk factors.
What this interaction means in plain words
Azithromycin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azithromycin belongs to Anti Bacterial; Telavancin belongs to Anti Bacterial.
Why it happens
Additive prolongation of cardiac repolarization.
What to do
Obtain a baseline ECG in patients with QT risk factors and monitor QTc and electrolytes. Choose a non-QT-prolonging alternative where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Frequently asked questions
Can I take Azithromycin with Telavancin?
MediHelp rates the interaction as moderate. Azithromycin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azithromycin can prolong the QTc interval and has been associated with torsades de pointes. With telavancin, the combined effect on repolarization may increase arrhythmia risk, especially with other risk factors.
How serious is the interaction between Azithromycin and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with QT risk factors and monitor QTc and electrolytes. Choose a non-QT-prolonging alternative where possible.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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